Advice from a Beethoven enthusiast and not from a pianist.
Opus 78!
Why?
Because it is a "little" gem of a Sonata and, as often happens with Beethoven's works, since it is considered "minor" in terms of scope and value, it was clamorously snubbed by a certain nineteenth-century criticism and... not only that!
But, in reality, as with the Eighth Symphony, it is a great Sonata.
Like the Eighth Symphony, it is a composition that lacks the heroic and muscular drive, typically Beethovenian, but, just like the Eighth Symphony, it was particularly loved by its composer to the point of responding, to those who asked him, that he much preferred Opus 78 over Opus 27 no. 2. And this is further demonstration that, despite everything, Beethoven greatly preferred this type of music.
Who knows? Perhaps also because this one was dedicated to Thérese, while the other to Giulietta and, the memory was more beautiful, but I think that once again, the composer may have had his own exquisitely musical reasons for stating this.
Still as a non-pianist but as a Beethoven enthusiast, I would exclude the other 3, because compared to Opus 78 and 27 no. 2, they remain on slightly lower steps.